Quantum field theory in curved spacetime is a vibrant field of research in physics, lying at the intersection of quantum theory, gravitation and mathematical physics. I will give my perspective on this field, an overview of its conceptual status inside physics and discuss some of the predictions of the theory, such as Hawking radiation and the Unruh effect. I will also comment on mathematical and experimental challenges lying ahead of the road on the subject. In the spirit of the seminar, the talk will be rather verbose and technicalities will be avoided.